Aquifer Pediatrics
Aquifer Pediatrics helps students develop clinical reasoning skills critical to becoming successful practitioners. Our virtual cases provide key content correlated to COMSEP’s learning objectives—a proven path to success in developing clinical reasoning skills.
The 32 interactive virtual patient cases in Aquifer Pediatrics deliver on the learning objectives of the Council on Medical Student Education in Pediatrics (COMSEP) clerkship curriculum.

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Embedded Curricular Threads
New embedded threads provide consistent teaching on interdisciplinary Clinical Excellence topics throughout Aquifer’s core courses. Select Family Medicine cases include new content woven into our existing cases to highlight key principles in palliative care, trauma-informed care, social determinants of health, high value care, diagnostic excellence, and foundations of telemedicine.
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Key Features
- Created for educators, by educators, to cover the full range of COMSEP’s curriculum
- Available for institutional subscription or for direct purchase by individual subscribers
- Access to Aquifer Calibrate: Transformative Assessments for Clinical Learning Mastery, our innovative system for formative assessment, available with your 2025-26 subscription
- Proven pedagogy that standardizes experiences—overcoming geography, seasonality, and accessibility
- Evidence-based, peer-reviewed, and continuously updated content
- Self-assessment questions emphasize key content and enable students to test their knowledge and skills
- A wealth of source material, tools, and full references in each case
- Course-specific student and educator resources, including active learning modules (TBL-style application exercises), interactive table of childhood developmental milestones, and a case analysis tool
- Delivered via the Aqueduct learning management system, which includes user management options, easy reporting on student progress and course usage, plus tools for creating custom courses to match a specific curriculum
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Course Content
With realistic case scenarios that demonstrate best practices, our course builds a bridge from content to practice for our students. Aquifer Pediatrics’ interactive virtual patient cases are based on the COMSEP curriculum. The cases ensure that students are exposed to all the various clinical scenarios, irrespective of location or time of year.
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Curriculum Integration
Aquifer Pediatrics can be used by third-year medical students, PA students, and Nurse Practitioner students as a complement to a clerkship or course on pediatrics.
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Assessment
Aquifer Calibrate, an innovative system for formative assessments, is available with your subscription to Aquifer Pediatrics. Calibrate combines the concepts of test-enhanced learning and distributed practice to facilitate efficient study planning and self-directed learning for students and identify at-risk students and curricular gaps for faculty.
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Case List
Pediatrics 01: Newborn infant evaluation and care
Pediatrics 02: Infant well-child visits (2, 6, and 9 months)
Pediatrics 03: 3-year-old well-child visit
Pediatrics 04: 8-year-old well-child check
Pediatrics 05: 16-year-old health maintenance visit
Pediatrics 06: 16-year-old preparticipation evaluation
Pediatrics 07: 2-hour-old newborn with respiratory distress
Pediatrics 08: 6-day-old with jaundice
Pediatrics 09: 2-week-old with lethargy
Pediatrics 10: 6-month-old infant with a fever
Pediatrics 11: 4-year-old with fever and adenopathy
Pediatrics 12: 10-month-old with a cough
Pediatrics 13: 6-year-old with chronic cough
Pediatrics 14: 18-month-old with congestion
Pediatrics 15: Two siblings: 4-year-old and 8-week-old with vomiting
Pediatrics 16: 7-year-old with abdominal pain and vomiting
Pediatrics 17: 4-year-old refusing to walk
Pediatrics 18: 6-week-old with poor feeding
Pediatrics 19: 16-month-old with first seizure
Neurology 10: Pediatrics 20: 7-year-old with headache
Pediatrics 21: 6-year-old with bruising
Pediatrics 22: 16-year-old with abdominal pain
Pediatrics 23: 15-year-old with lethargy and fever
Pediatrics 24: 2-year-old with altered mental status
Pediatrics 25: 2-month-old with apnea
Pediatrics 26: 9-week-old not gaining weight
Pediatrics 27: 8-year-old with abdominal pain
Pediatrics 28: 18-month-old with developmental delay
Pediatrics 29: Infant with hypotonia
Pediatrics 30: 2-year-old with sickle cell disease
Pediatrics 31: 5-year-old with puffy eyes
Pediatrics 32: A day in pediatric dermatology clinic
User Story
Learn how Aquifer Pediatrics can benefit medical students and faculty in your program.
Robert Drucker, MD
Duke University
I like that these cases are real-life scenarios and very applicable to the patients I see in clinic with my mentors. I feel just by doing these cases in a few days, my experience in family medicine has improved by leaps and bounds and my mentors can see a marked improvement and change in me, even down to how I interact with patients and present myself. Thank you so much Aquifer, you're a lifesaver!
Educator Guide Available
The Educator Guide—available to all subscribers—provides a quick reference guide for all cases, resources, and features included with Aquifer Pediatrics. The Educator Guide is ideal for educators who are getting started using Aquifer, or experienced users who want to be sure they are taking advantage of Aquifer’s extensive resources and tools.
Active Learning Modules
These team-based learning exercises have been thoughtfully prepared with the aim of minimizing teacher preparation time and maximizing learner achievement. Learn more about the Pediatrics Active Learning Modules.
- Fever Module
- Immunizations Module
- Patient Safety Module
- Child Development Module
Case Analysis Tool
The toolkit contains a structured worksheet completed by the students as they work through the virtual patient case, designed to enhance the development of clinical reasoning skills. Each step mirrors the process through which clinicians gather and process information about a patient, leading up to the development of an initial evaluation and treatment plan. Answer keys are included for most cases. Learn more about the Case Analysis Tool.
Aquifer Pediatrics Course Board
Patricia McBurney, MD, MSCR
Course Board: Aquifer Pediatrics
Role: Associate Editor and Assessment Lead
Institution: Medical University of South Carolina
Institutional Title: Professor
Institutional Role: Co-Director, Pediatric Clerkship
Erin McMaster, MD
Course Board: Aquifer Family Medicine
Role: Editor-in-Chief
Former Roles: Curriculum Lead, Case Author, Associate Editor
Cases Authored: Family Medicine 05: 30-year-old woman with palpitations
Institution: Perelman School of Medicine at the University of Pennsylvania
Institutional Title: Associate Professor Emeritus
Kirstin Nackers, MD
Current Role: Academic Director of Assessment
Former Role: Editor-in-Chief
Course Board: Aquifer Pediatrics
Institution: University of Wisconsin School of Medicine and Public Health
Lavjay Butani, MD
Course Board: Aquifer Pediatrics
Role: Associate Editor
Institution: UC Davis Health
Institutional Title: Vice Chair for Academic Affairs, Department of Pediatrics, Chief Division of Nephrology
Mentoring Director, Department of Pediatrics
Director of Student Development, Office of Medical Education
Professor, Department of Nephrology
Institutional Role: Pediatric Nephrology
Emily Graham, MD
Course Board:Aquifer Pediatrics
Role: Associate Editor
Institution: The Ohio State University Wexner Medical Center
Institutional Title: Clinical Assistant Professor
Institutional Role: Director of Competency for the Patient Care Curriculum
Part 2 Unit Director
Internal Medicine Clerkship
Elizabeth Espinoza, DNP, CPNP-AC
Course Board: Aquifer Pediatrics
Role: Associate Editor
Institution: Oregon Health Science University Pediatric Nurse Practitioner Program
Institutional Title: Assistant Professor of Nursing
Kanika Gupta, MD, FAAP
Course Board: Aquifer Pediatrics
Role: Associate Editor
Institution: Nemours Children’s Health
Institutional Title: Pediatric Hospitalist
Institutional Role: Associate Program Director, PHM Fellowship
Joan Connell, MD, MPH, FAAP
Course Board: Aquifer Pediatrics
Role: Associate Editor
Institution: University of North Dakota School of Medicine
Institutional Title: Clinical Professor, Pediatrics, Associate Professor, Family Medicine
Institutional Role: Pediatrics
Aleisha Nabower, MD, MHPTT
Course Board: Aquifer Pediatrics
Role: Associate Editor
Institution: University of Nebraska Medical Center
Institutional Title: Associate Professor, Pediatrics
Sandy Narciso-Owen, MS, MSPAS, PA-C
Course Board: Aquifer Pediatrics
Role: Associate Editor
Institution: Sacred Heart University Physician Assistant Studies Program
Institutional Title: Clinical Assistant Professor, Director of Didactic Education, Director of Simulation, Chair of Admissions
Lori Singleton, MD, FAAP
Course Board: Aquifer Pediatrics
Role: Associate Editor
Institution: Morehouse School of Medicine
Institutional Title: Associate Professor of Pediatrics
Mark Harrison, MD
Course Board: Aquifer Pediatrics
Role: Associate Editor
Institution: Kansas University Medical Center
Institutional Title: Associate Professor
Institutional Role: Pediatrics Clerkship Director, MS3 Pediatrics Clerkship Director